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It's hard not to get excited about news of a potentially effective treatment for sepsis, a condition that leads to multiple organ failure and kills more people in the hospital than any other disease.

But there have been so many false promises about this condition over the years, it's also wise to treat announcements — like one published online by the journal, Chest — with caution.

The Internet Movie Database (IMDb) has adopted the F-rating, a classification system designed to champion women in film.

The new rating was created three years ago by Holly Tarquini, executive director of the Bath Film Festival, to "support women in film and change the stories we see on screen." The Bath festival created a website for the rating, which says:

"The F-Rating is a classification for any film which

  1. is directed by a woman
  2. is written by a woman

In August 2016, an outbreak of mumps began in Arkansas. Since then, there have been nearly 3,000 cases of the disease across 33 counties in the state.

As a public health practitioner, I wondered: Why did this outbreak take off?

My team at HealthMap, a computational epidemiology lab based out of Boston Children's Hospital, began by rounding up as much data as we could.

The Affordable Care Act replacement plan championed by President Trump would hurt low-income people in rural areas that voted heavily for the Republican last fall, according to an NPR analysis of data on proposed subsidy changes from the Kaiser Family Foundation.

Dan Fazio says his phone is "ringing off the hook" these days.

He's executive director of WAFLA, an organization that helps fruit growers in Washington state find workers — and specifically, foreign workers who are allowed to enter the U.S. specifically as seasonal workers on farms.

Musicians from all over the world are settling back at home, recovering from last week's South by Southwest festival in Austin, Texas. Hundreds of musicians played throughout the week, for crowds big and small.

It's not every day that the world gets a new tool that could save 100,000 children each year.

And it's definitely not every day that the secret to that tool is the same thing that makes space ice cream so memorable.

Sounds crazy. But bear with me a moment.

Scientists say they have a new vaccine that's about 70 percent effective against rotavirus — a nasty little pathogen that gives children bad diarrhea here in the U.S. but kills more than 200,000 children each year in developing countries.

Sears used to be the titan of American retailing. But now its future is in doubt.

Shares of the company's stock tumbled 12 percent today after the company acknowledged Tuesday in its annual 10-K filing that its future viability is not a sure thing. A 10-K is a report that public companies file with the Securities and Exchange Commission, giving a comprehensive summary of the company's financial performance.

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

AUDIE CORNISH, HOST:

A short update now on an attack in London today that police there are calling a terrorist incident.

KELLY MCEVERS, HOST:

At the State Department on Wednesday, officials from 68 countries and organizations gathered for a two-day summit to coordinate plans to fight ISIS. This was the first full meeting of the Global Coalition on the Defeat of ISIS since 2014, and a chance for the Trump administration to flesh out what it wants to do differently.

So far, it is mainly stepping up a fight that the Obama administration put in motion.

For the first time in birds, researchers say they have found evidence that a New Zealand parrot has the avian equivalent of an infectious laugh.

They call it "positive emotional contagion" — which they define as "outwardly emotional actions that spread from one individual to another." In humans, this is what happens when one person hears another laugh and also starts cracking up.

Angela Chen makes money hawking her ties to important people, running a consulting firm that helps companies connect with Asia's power players.

So it inevitably attracted notice when Chen spent nearly $16 million recently to buy a four-bedroom Park Avenue penthouse owned by President Trump himself.

The February deal, which was first reported by Mother Jones, underscores one of the problems posed by Trump's ongoing business interests.

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

KELLY MCEVERS, HOST:

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

AUDIE CORNISH, HOST:

During the presidential campaign, Donald Trump's outreach to black voters essentially came down to this.

(SOUNDBITE OF ARCHIVED RECORDING)

Before Carmencita Misa became bedridden, she was a veritable "dancing queen," says her daughter, Charlotte Altieri.

"Even though she would work about 60 hours a week, she would make sure to go out dancing once a week — no matter what," Altieri, says. "She was the life-of-the-party kind of person, the central nervous system for all her friends."

A massive stroke in March 2014 changed all that. It robbed Misa, 71, of her short-term memory, her eyesight and her mobility — and it left her dependent on a feeding tube for nourishment. Now, she lives in a nursing home.

An airstrike by U.S.-led coalition forces leveled a school west of Raqqa and killed at least 33 people, according to two activist groups monitoring Syria. The groups allege the attack, which they say occurred overnight on Monday and Tuesday, hit a building that had been housing families fleeing violence in war-torn areas nearby.

Updated at 7:12 p.m. ET

Explosive accusations and countercharges on Wednesday threatened to derail one of Congress' investigations into the potential connections between President Trump's 2016 campaign aides and Russia's meddling in the election.

The Republican chairman of the House Intelligence Committee, Rep. Devin Nunes of California, announced that he had learned that then-President-elect Donald Trump and some of his staff had been caught up in U.S. surveillance of foreign targets overseas in the months after the election.

Actor Woody Harrelson has played a number of dramatic parts in the past few years in “The Hunger Games” films, the HBO series “True Detective” and his Oscar-nominated turn in “The Messenger.”

But as the title character in the new film “Wilson” (@WilsonMovie), Harrelson plays a man with no filter, who has no qualms about telling total strangers his life story. As he tells Here & Now‘s Robin Young, the role is a welcome return to comedy.

S&P And Dow See Worst Drops In 5 Months

Mar 22, 2017

The S&P 500 and Dow Jones Industrial Average both fell by around 1 percent Tuesday, for the first time in five months. Many investors saw the drops as a sign of doubts about whether President Trump will be able to accomplish tax cuts or infrastructure spending.

Here & Now‘s Jeremy Hobson speaks with CNN’s Maggie Lake (@maggielake) about what we can take from market moves this week.

High school juniors and seniors are well into their college preparation — taking the SAT, visiting schools and filling out applications. But it’s not too early for sophomores to start planning.

Here & Now‘s Jeremy Hobson gets some tips on what 10th-graders — and their parents — should be thinking about from Lisa Micele (@LisaMicele), director of college counseling at the University of Illinois Laboratory High School in Urbana, Illinois.

Thursday will mark seven years since President Obama signed the now-threatened Affordable Care Act before a crowd in the jam-packed East Room of the White House. It was the signature legislative moment of his presidency, underscored by then-Vice President Biden, who whispered into the president's ear that it was a "big f****** deal." The mic picked up the remark, which created quite a stir.

The Food and Drug Administration says at least nine women have died of a rare blood cancer after receiving breast implants, and that the agency is officially acknowledging an association between the implants and the disease.

On Tuesday, the agency announced that as of Feb. 1, it had received 359 breast implant-associated reports of a rare type of non-Hodgkin's lymphoma called anaplastic large cell lymphoma, or ALCL.

By a largely party-line vote Tuesday, the Senate approved a bill that repeals Obama-era hunting restrictions on national wildlife refuges in Alaska. The House already voted last month to abolish those restrictions — which were instituted by the Fish and Wildlife Service in 2016 to protect predator species from hunters — and so the bill now heads to the desk of President Trump, who is widely expected to sign it.

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

RACHEL MARTIN, HOST:

School districts must give students with disabilities the chance to make meaningful, "appropriately ambitious" progress, the Supreme Court said Wednesday in an 8-0 ruling.

The decision in Endrew F. v. Douglas County School District could have far-reaching implications for the 6.5 million students with disabilities in the United States.

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

DAVID GREENE, HOST:

Updated at 4:30 a.m. ET Thursday

British authorities have made eight arrests in their investigation into Wednesday's attack in London, police said Thursday morning.

Mark Rowley, the national lead for counterterrorism policing, told reporters that there were four dead, including the attacker, and 29 people have been treated in hospitals. Seven people are in critical condition, he said.

Police had earlier said there were five dead including the attacker.

North Korea fired a missile from its east coast Wednesday, in a test that appears to have failed in an explosion within seconds of launch, according to the South Korean Defense Ministry and U.S. Pacific Command. Both groups confirm the launch occurred at North Korea's air base in Wonsan.

The ill-fated missile, which marks the country's third test of the year and second so far this month, is seen as a response to annual joint military drills by the U.S. and South Korea.

Copyright 2017 NPR. To see more, visit http://www.npr.org/.

RACHEL MARTIN, HOST:

Two men who were born in Germany but don't have German citizenship will be deported to countries in North Africa, where their parents immigrated from, over suspicions that they were planning a terrorist attack. German officials say it's the first time the government is making such a move.

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